P.089 Ultra-high frequency deep brain stimulation at 10,000 Hz improves motor function
نویسندگان
چکیده
منابع مشابه
Clustered Desynchronization from High-Frequency Deep Brain Stimulation
While high-frequency deep brain stimulation is a well established treatment for Parkinson's disease, its underlying mechanisms remain elusive. Here, we show that two competing hypotheses, desynchronization and entrainment in a population of model neurons, may not be mutually exclusive. We find that in a noisy group of phase oscillators, high frequency perturbations can separate the population i...
متن کاملHigh Frequency Deep Brain Stimulation and the Urine Storage Function in Awake Pigs
Methods In 6 female Goettingen minipigs (weight 22–47 kg), 5 of which had been intoxicated with 1-methyl-4-phenyl1,2,3,6-tetrahydropyridine (MPTP), a unilateral electrode for chronic stimulation was placed in the subthalamic area. Correct localization of the electrode was verified by peroperative MRI-scan and examined by autopsy at study-termination after 12-14 months of stimulation-treatment. ...
متن کاملMedial septal nucleus theta frequency deep brain stimulation improves spatial working memory after traumatic brain injury.
More than 5,000,000 survivors of traumatic brain injury (TBI) live with persistent cognitive deficits, some of which likely derive from hippocampal dysfunction. Oscillatory activity in the hippocampus is critical for normal learning and memory functions, and can be modulated using deep brain stimulation techniques. In this pre-clinical study, we demonstrate that lateral fluid percussion TBI res...
متن کاملO10: Deep Brain Stimulation and Psychiatry
The use of deep brain stimulation in psychiatric disorders has received great interest owing to the small risk of the operation, the reversible nature of the technique, and the possibility of optimizing treatment postoperatively. Currently deep brain stimulation in psychiatry is investigated for obsessive-compulsive disorder, Gilles de la Tourette’s syndrome and major depression. This presentat...
متن کاملControl of epileptic seizures by electrical low frequency deep brain stimulation: A review of probable mechanisms
Epilepsy is the most common neurological disease with no definitive method in treatment. Notably, the main way to treat and control epileptic seizures is drug therapy. However, about 20-30% of patients with epilepsy are drug resistant and require other therapeutic manners. Deep brain stimulation is a new therapeutic strategy for these patients. Conspicuously, there are no clear answers for basi...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques
سال: 2019
ISSN: 0317-1671,2057-0155
DOI: 10.1017/cjn.2019.184